What is chloroquine?

Chloroquine is a medication to treat or prevent malaria, a disease caused by parasites. This medicine works by interfering with the growth of parasites in the red blood cells of the human body.

Parasites that cause malaria typically enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia.

Chloroquine is used to treat and to prevent malaria. Chloroquine is also used to treat infections caused by amoebae.

Chloroquine may also be used for purposes not listed in this medication guide.

What is the most important information I should know about chloroquine?

You should not use this medication if you are allergic to chloroquine or hydroxychloroquine (Plaquenil), or if you have a history of vision changes or damage to your retina caused by chloroquine or similar anti-malaria medications.

Before you take chloroquine, tell your doctor if you have psoriasis, porphyria, liver disease, alcoholism, G6PD deficiency, or a history of problems with your vision or hearing.

Some people taking this medication over long periods of time or at high doses have developed irreversible damage to the retina of the eye. Stop taking chloroquine and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes.

This medication may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Call a poison control center at once and then seek emergency medical attention if you think you have used too much of this medicine. An overdose of chloroquine can be fatal, especially in children.

What should I discuss with my healthcare provider before taking chloroquine?

You should not use this medication if you are allergic to chloroquine or hydroxychloroquine (Plaquenil), or if you have a history of vision changes or damage to your retina caused by chloroquine or similar anti-malaria medications.