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Nitrazepam belongs to a group of medicines called benzodiazepines. It acts on receptors in the brain (GABA receptors) causing the release of a chemical called GABA (gamma amino butyric acid). GABA is a major inhibitory chemical in the brain involved in inducing sleepiness and control of anxiety and fits.
Nitrazepam acts by increasing the activity of GABA, thereby reducing the functioning of certain areas of the brain. This results in sleepiness, a decrease in anxiety and relaxation of muscles.
Nitrazepam is most commonly used to treat insomnia. It decreases the time taken to fall asleep and nocturnal awakenings, as well as increasing the total amount of time spent sleeping. As nitrazepam remains active in the body for many hours, drowsiness may occur the next day.
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